Читать книгу Super Human: The Bulletproof Plan to Age Backward and Maybe Even Live Forever онлайн

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But the more likely reason your cells fill up with junk is that you eat too many foods that your lysosomes are incapable of incinerating even if they are functioning perfectly. These are advanced glycation end products (AGEs) that you eat rather than the ones that are made by sugar inside your body. Remember when I said that when sugar and proteins link up inside your body, it is the same as caramelizing onions? Yeah, it also happens when you eat caramelized protein: aka charred meat (from grilling over an open flame, broiling, or cooking protein with sugars). The AGEs you consume get stuck inside your cells, and your lysosomes can’t clear them out.

Over time, these materials build up, making more and more of your cells dysfunctional, and this affects your ability to control blood sugar levels²⁶ and increases your risk of cancer²⁷ and heart disease.²⁸ When it happens to neurons, it can contribute to Alzheimer’s.²⁹

Fried, blackened, and charred meat all contain tons of AGEs that can overload your cellular waste system and leave your cells literally full of garbage. And this dramatically raises your risk of developing one or more of the Four Killers. A 2019 study published in BMJ looked at the dietary habits of over one hundred thousand women between the ages of fifty to seventy-nine over the course of several years. After taking into account potentially influential factors such as lifestyle, overall diet quality, education level, and income, the researchers found that regularly eating fried foods (which also contain AGEs, since frying produces a similar chemical process as charring meat) was associated with a heightened risk of death from any cause and, specifically, heart-related death. Those who ate just one or more servings of fried food a day had an 8 percent higher risk of death from heart disease than those who did not eat fried food. One or more servings of fried chicken a day specifically was linked to a 13 percent higher risk of death from any cause and a 12 percent higher risk of heart-related death than someone who ate no fried food.³⁰