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Fasting has profound effects, even at less than fifty-eight hours. Alternative day fasting, a form of intermittent fasting in which you eat every other day, helps prevent chronic disease and reduce triglyceride and low-density lipoprotein (LDL) cholesterol levels in as little as eight weeks.15 Intermittent fasting also increases your brain’s ability to grow and evolve by boosting neuronal plasticity (the brain’s ability to change throughout your life) and neurogenesis (the birth of new neurons).16 This can help ward off Alzheimer’s and cognitive decline.

As you might expect, when I started experimenting with intermittent fasting ten years ago, I was often left feeling cranky and cold around lunchtime, before my eating window opened. This is because I had not yet developed the metabolic flexibility from teaching my body to efficiently burn carbohydrates or fat. Today I can effortlessly fast for twenty-four hours because my metabolism is younger and my blood sugar levels have stabilized. Thankfully, there are now well-understood ways to make intermittent fasting painless, which you’ll read about later.

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